The prefrontal cortex: Projection area of the thalamic mediodorsal nucleus?
نویسندگان
چکیده
منابع مشابه
The prefrontal cortex: Projection area of the thalamic mediodorsal nucleus?
The historical bases of the definitions of the prefrontal cortex are reviewed (cytoarchitecture, electrical unexcitability, afferents from the mediodorsal thalamic nucleus). Evidence is presented that the widely accepted proposal of Rose and Woolsey (1948) to name all cortex prefrontal that is reached by afferents from the mediodorsal nucleus is questionable for three reasons: the diversity of ...
متن کاملCortical projections of the thalamic mediodorsal nucleus in the rat. Definition of the prefrontal cortex.
Deposits of somatopetal tracers, that filled the entire dorsolateral cortex of one hemisphere, labelled only a few cell bodies in the thalamic mediodorsal nucleus (MD). Further experiments served to confirm the existence of strong projections from MD to the mesial and suprarhinal areas of the frontal cortex. Thus, only a very small proportion of the MD neurones in the rat projects outside the c...
متن کاملDistribution of mediodorsal thalamic nucleus afferents originating in the prefrontal association cortex of the dog.
The nediodorsal thalamic nucleus (MD) afferents originating in the prefrontal cortex (PFC) were studied in 14 dogs, using the method of retrograde horseradish peroxidase transport. Injections limited to small areas of MD indicated that projection between MD and PFC shows precise topography and reciprocity. However, the distribution of labeled neurons suggests a division of MD into two main segm...
متن کاملThalamic mediodorsal nucleus and its participation in spatial working memory processes: comparison with the prefrontal cortex
Working memory is a dynamic neural system that includes processes for temporarily maintaining and processing information. Working memory plays a significant role in a variety of cognitive functions, such as thinking, reasoning, decision-making, and language comprehension. Although the prefrontal cortex (PFC) is known to play an important role in working memory, several lines of evidence indicat...
متن کاملThe mediodorsal thalamic nucleus and schizophrenia.
The mediodorsal nucleus of the human thalamus is in a crucial position that allows it to establish connections with diverse cerebral structures, particularly the prefrontal cortex. The present review examines existing neurobiologic studies of the brains of people with and without schizophrenia that indicate a possible involvement of the mediodorsal nucleus in this psychiatric disorder. Studies ...
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ژورنال
عنوان ژورنال: Physiological Psychology
سال: 1979
ISSN: 0090-5046
DOI: 10.3758/bf03326611